There are no clinical signs or symptoms characteristic of gall bladder cancer. Jaundice (the skin turning yellow), bloating, abdominal pain, weight loss, decreasing appetite, fever, nausea or an enlarging abdominal mass are all signs that may be attributable to gall bladder cancer. Frequently, jaundice is a late development and the other symptoms have been present for a long time. Itching may result from the buildup in the skin of a derivative of bile, bilirubin, which turns the skin yellow. This symptom usually reflects advanced disease.
